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Migraines and Chronic Fatigue in Adolescents
SEATTLE (Ivanhoe Newswire) -- New research shows adolescents with
unexplained chronic fatigue syndrome (CFS) have higher rates of school
absenteeism than adolescents with migraines or healthy adolescents. These
adolescents also have higher rates of depression and somatization, or
recurring complaints that are not caused by any real physical illness.
In the study, 179 adolescents, ages 11 to 18, were referred to Children's
Hospital and Regional Medical Center in Seattle for behavioral treatment
of a migraine. They were compared to 97 adolescents who were referred for
chronic fatigue evaluation as well as 32 healthy adolescents.
Participants were given several tests and were asked to estimate how many
school days they missed in the past six months because of illness.
Results of the study show adolescents with chronic fatigue had
significantly higher scores on depression and somatization tests than the
healthy adolescents or those with migraines. However, adolescents with
migraines had significantly higher anxiety scores than the other groups.
Adolescents with chronic fatigue syndrome missed more school days than
adolescents with migraines, but adolescents with migraines missed more
school days than healthy children.
Results of the study show parents of adolescents with chronic fatigue
were less likely to endorse psychological factors as a possible
contributor to their children's symptoms than parents of adolescents in
the other groups.
Researchers say unexplained chronic fatigue is relatively uncommon in
adolescence and rare in childhood. Experts say it is a perplexing problem
for pediatricians.
This article was reported by Ivanhoe.com, who offers Medical Alerts by
e-mail every day of the week. To subscribe, go to:
www.ivanhoe.com/newsalert/. SOURCE: Pediatrics, 2003;111:e376-e381
Copyright © 2003 Ivanhoe Broadcast News, Inc.
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PubMed Abstract
Pediatrics 2003 Apr;111(4 Pt 1):e376-81 Related Articles, Links
Comparative study of anxiety, depression, somatization,
functional disability, and illness attribution in adolescents with
chronic fatigue or migraine.
Smith MS, Martin-Herz SP, Womack WM, Marsigan JL.
Children's Hospital & Regional Medical Center, Department of
Pediatrics, University of Washington, Seattle 98105, USA.
mark.smith@s...
OBJECTIVE: To compare adolescents with migraine, unexplained
profound chronic fatigue of >6 months duration, and normal school
controls on measures of anxiety, depression, somatization, functional
disability, and illness attribution. METHODS: Adolescents referred to
Children's Hospital and Regional Medical Center for behavioral
treatment of migraine (n = 179) or evaluation of chronic fatigue
(n = 97) were compared with a group of healthy controls of similar
age and sex from a middle school (n = 32). Subjects completed the
Spielberger State-Trait Anxiety Inventory-Trait Form, the Children's
Depression Inventory, the Childhood Somatization Inventory, and
estimated the number of school days missed in the past 6 months because
of illness. Migraine and fatigued subjects completed an illness
attribution questionnaire. RESULTS: Subjects in the 3 groups were
56% to 70% female and ranged from 11 years old to 18 years old with
a mean age of 14.0 2.0. Forty-six of the 97 chronically fatigued
adolescents met 1994 Centers for Disease Control and Prevention (CDC)
criteria for chronic fatigue syndrome (CDC-CFS), while 51 had idiopathic
chronic fatigue syndrome (I-CFS) that did not meet full CDC criteria.
Adolescents with migraine had significantly higher anxiety scores than
those with I-CFS or controls and higher somatization scores than
controls. Adolescents with CDC-CFS had significantly higher anxiety
scores than those with I-CFS or controls, and higher depression and
somatization scores than all other groups. There were significant
differences between all groups for school days missed with CDC-CFS
more than I-CFS more than migraine more than controls. Parents of
adolescents with unexplained I-CFS had significantly lower attribution
scores relating illness to possible psychological or stress factors
than parents of adolescents with CDC-CFS or migraine. CONCLUSIONS:
Adolescents referred to an academic center for evaluation of
unexplained chronic fatigue had greater rates of school absenteeism
than adolescents with migraine or healthy controls. Those meeting
CDC-CFS criteria had higher anxiety scores than controls and higher
depression and somatization scores than migraineurs or controls.
Parents of adolescents with I-CFS were less likely to endorse
psychological factors as possibly contributing to their symptoms
than parents of adolescents with CDC-CFS or migraine.
PMID: 12671155 [PubMed-in process]
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