Adding to the credibility of Dr. Cheney's anoxic cerebral edema theory, Australian and British researchers have independently confirmed that the muscles of
many CFS patients produce twice the normal amount of lactic acid during exercise. Lactic acid is produced by muscles when they metabolize glucose (sugar) in
the absence of sufficient oxygen. Some CFS patients are unable to metabolize glucose effectively, thus causing a kind of "glucose intolerance." Their
muscles turn glucose into lactic acid which poisons the system, thus causing extreme fatigue and weakness. Additional research has also found high lactic acid
levels within the cerebral spinal fluid of CFS patients as well. - See links section #6.
Research at both Vanderbilt University and the Mayo Clinic confirms that most people with POTS have reduced renin production. Renin is a protein-digesting enzyme that is released by the kidneys and acts to raise blood pressure by activating angiotensin, a powerful vasoconstricting hormone. This finding suggests a general breakdown of the autonomic nervous system, which regulates the body's basic physical systems automatically. The end result of this dysregulation is less blood and oxygen getting to the brain (brain hypoxia).
home.att.net/~potsweb/theories.html
====
www.increase-your-energy..../cfs.html.
POSSIBLE CAUSES:
Mitochondria
Seventy percent of people with CFS have been shown to have defective mitochondria in their cell.
Reduced Blood Flow
Enlarged, misshapen blood cells combined with smaller capillary size decreases the body's ability to transport oxygen within the circulatory system. Lack of oxygen
may explain discomfort caused by tissue deterioration in CFS patients. The small capillaries in the Central Nervous System (CNS) are more susceptible to change in blood molecule size and shape. Diagnostic scans on the hypothalamus in the brain show patterns of reduced blood flow in CFS patients, breaking down CNS functioning and nerve signal processing.
Neuroendocrine dysfunction
Ion channels responsible for the process of conduction between the hypothalamus (responsible for hormone regulation) and the brain stem show signs of abnormalities in patients with CFS. There may be a correlation between these abnormalities, impaired blood flow, and regenerative functions in the body.
Viruses
A common history of many CFS patients is the development of severe illness before the onset of CFS. Research continues to draw connections between CFS and patients infected with different strains of herpes, enteroviruses or retroviruses. CFS could be a reaction and biological breakdown in the immune system after infection with these relatively common viruses.
Diet
Low levels of L-Carnitine and Acetyl L-Carnitine have been shown in CFS patients.
Environmental Toxins
There is research that points to environmental contamination as the cause of CFS symptoms.
Stress
While it is clear that emotional and physical stresses do amplify CFS symptoms, there is no biological evidence to support either as causing CFS. Tests done on CFS and Depression patients show difference in neurological functioning and body chemistry that exclude a relation of the two.
Although its origins remain unknown, CFS is a very real disease, and requires medical attention.
Research at both Vanderbilt University and the Mayo Clinic confirms that most people with POTS have reduced renin production. Renin is a protein-digesting enzyme that is released by the kidneys and acts to raise blood pressure by activating angiotensin, a powerful vasoconstricting hormone. This finding suggests a general breakdown of the autonomic nervous system, which regulates the body's basic physical systems automatically. The end result of this dysregulation is less blood and oxygen getting to the brain (brain hypoxia).
home.att.net/~potsweb/theories.html
====
www.increase-your-energy..../cfs.html.
POSSIBLE CAUSES:
Mitochondria
Seventy percent of people with CFS have been shown to have defective mitochondria in their cell.
Reduced Blood Flow
Enlarged, misshapen blood cells combined with smaller capillary size decreases the body's ability to transport oxygen within the circulatory system. Lack of oxygen
may explain discomfort caused by tissue deterioration in CFS patients. The small capillaries in the Central Nervous System (CNS) are more susceptible to change in blood molecule size and shape. Diagnostic scans on the hypothalamus in the brain show patterns of reduced blood flow in CFS patients, breaking down CNS functioning and nerve signal processing.
Neuroendocrine dysfunction
Ion channels responsible for the process of conduction between the hypothalamus (responsible for hormone regulation) and the brain stem show signs of abnormalities in patients with CFS. There may be a correlation between these abnormalities, impaired blood flow, and regenerative functions in the body.
Viruses
A common history of many CFS patients is the development of severe illness before the onset of CFS. Research continues to draw connections between CFS and patients infected with different strains of herpes, enteroviruses or retroviruses. CFS could be a reaction and biological breakdown in the immune system after infection with these relatively common viruses.
Diet
Low levels of L-Carnitine and Acetyl L-Carnitine have been shown in CFS patients.
Environmental Toxins
There is research that points to environmental contamination as the cause of CFS symptoms.
Stress
While it is clear that emotional and physical stresses do amplify CFS symptoms, there is no biological evidence to support either as causing CFS. Tests done on CFS and Depression patients show difference in neurological functioning and body chemistry that exclude a relation of the two.
Although its origins remain unknown, CFS is a very real disease, and requires medical attention.
USA
