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I was just going to post something to you Gail, and then I saw this.....I've been following this whole endocrine thing for so long, I'm starting to have to re-file all of my stacks and stacks of paperwork.

A long time ago I read that thyroid problems cause pain in the upper back, shoulders, neck.
Problems with the adrenal function causes pain in the lower limbs, hips, lower back.
Since I've got both, I got lucky, huh?

NOTE:
08-04-2003

By Rich Van Konynenburg, Ph.D.
Firdhaus Dhabhar is an Associate Professor at Ohio State University. His talk (at the NIH Workshop on CFS on June 12, 2003 at Bethesda, MD) had one central message, which was that under normal circumstances the effect of stress on the immune system is beneficial, not detrimental.
In conditions of short-term or acute stress, the response of the HPA axis is to raise the output of glucocorticoids for a short time, and this actually mobilizes the immune system to be better able to cope with incoming threats. For example, under these circumstances the white blood cell count in the peripheral blood decreases, but this does not mean that these cells have been destroyed. Rather, the white cells are moved out of the blood into the tissues to be ready to fight injuries or infections that may occur. Prof. Dhabhar used the picturesque language of warriors moving from their barracks to the boulevards, and from there to their battle positions.
He noted that the problems with stress and the immune system occur when the stress situation is long-term, as in weeks, months, or years. If the glucocorticoid output is maintained at a high level for such long times, the immune system is suppressed, as was discussed by Esther Sternberg.
I think that the significance of this talk for CFS is that while it appears that a history of high stress is important in bringing about the onset of CFS in many PWCs, this stress must be of long duration in order to have this effect. I think this is fully consistent with the stress history reported by many PWCs.

For the past month since I've been on dr. shoemakers staph phage lysate, I have been so very, very ill....And the pain has been absoluetly fierce. But in a way it was helpful because I was truly able to define this pain as a "toxic" pain. It is kind of described above. For me at least, the migratory traveling kind of pain that people have a hard time defining is worse when in a flare (duh) but it truly represents this toxicity that I feel.
I feel as if the pain is poisonous? Does that make sense to anyone.
And every where I read, whenever they refer to the endocrine invovelment, they refer then to this neurotoxicity type pain. I believe we become toxic and the pain would go away if we could find and route out this intruder that has invaded our bodies.

You have been such a Godsend to eveyone here, Gail, but especially to me in the past several months as my researching has waxed and waned as I became sicker. Thank you so much from the bottom of my heart for the encouragement......

Lanelle